Meny

Javascript verkar inte påslaget? - Vissa delar av Lunds universitets webbplats fungerar inte optimalt utan javascript, kontrollera din webbläsares inställningar.
Du är här

The evolution of immunity in relation to colonization and migration

Författare:
  • Emily A. O’Connor
  • Charlie K. Cornwallis
  • Dennis Hasselquist
  • Jan Åke Nilsson
  • Helena Westerdahl
Publiceringsår: 2018-05
Språk: Engelska
Sidor: 841-849
Publikation/Tidskrift/Serie: Nature Ecology and Evolution
Volym: 2
Nummer: 5
Dokumenttyp: Artikel i tidskrift
Förlag: Nature Publishing Group

Abstract english

Colonization and migration have a crucial effect on patterns of biodiversity, with disease predicted to play an important role in these processes. However, evidence of the effect of pathogens on broad patterns of colonization and migration is limited. Here, using phylogenetic analyses of 1,311 species of Afro-Palaearctic songbirds, we show that colonization events from regions of high (sub-Saharan Africa) to low (the Palaearctic) pathogen diversity were up to 20 times more frequent than the reverse, and that migration has evolved 3 times more frequently from African- as opposed to Palaearctic-resident species. We also found that resident species that colonized the Palaearctic from Africa, as well as African species that evolved long-distance migration to breed in the Palaearctic, have reduced diversity of key immune genes associated with pathogen recognition (major histocompatibility complex class I). These results suggest that changes in the pathogen community that occur during colonization and migration shape the evolution of the immune system, potentially by adjusting the trade-off between the benefits of extensive pathogen recognition and the costs of immunopathology that result from high major histocompatibility complex class I diversity.

Keywords

  • Ecology
  • Evolutionary Biology

Other

Published
  • Centre for Animal Movement Research
  • Molecular Ecology and Evolution Lab
  • ISSN: 2397-334X
Emily O'Connor
E-post: emily [dot] oconnor [at] biol [dot] lu [dot] se

Postdoc

MEMEG

+46 46 222 37 22

E-B275

50